Iranian Journal of Pediatrics 1995. 5(19):197-205.

Myositis Ossificans Progressiva
Jannati J, Samadi M

Abstract


Myositis Ossificans Progressiva (MOP) is a rare heritable disorder characterized by congenital skeletal abnormalities and progressive ectopic ossification of connective tissue. The cause of MOP is unknown and there is no known effective treatment. The course is inevitable slow progression in the extent of involvement and increasing loss of motor function until the patient is practically handicapped. In this article an 11-year old boy is presented in whom the signs and symptoms of MOP started since he was 5 months old. He showed bands of ossification in neck, over the vertebral column, shoulder, ankle and hip joints with restriction of movement in the involved joints as well as hypoplasia of the big toes and bilateral hallux valgus.

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