Differential diagnosis of metabolic Alkalosis

Abstract

A 9-month old female infant with growth retardation, constipation and restlessness id presented. Laboratory findings revealed hypochloremic metabolic alkalosis with hypokalemia and hyponatremia. Clinical and laboratory findings led us to think of batter syndrome and cystic fibrosis. Serum and urine levels of chloride were low. This led to the estimation of sweat electrolytes, which showed high chloride levels. Taking also into account other laboratory and clinical parameters cystic fibrosis was the final diagnosis.